|
|
p-coumaric_acid + CoA + ATP <=> 4-coumaroyl-CoA + AMP + diphosphate
|
6.2.1.12
4-coumarate---CoA ligase
6.2.1.2
medium-chain acyl-CoA ligase
6.2.1.30
phenylacetate---CoA ligase
|
–
–
–
|
| |
BRENDA:
BR63
KEGG:
R01616
MetaCyc:
4-COUMARATE--COA-LIGASE-RXN
SABIO-RK:
1761
|
|
|
|
2,4-dihydroxycinnamoyl-CoA <=> umbelliferone + CoA
|
not assigned
|
–
|
| |
KEGG:
R12310
MetaCyc:
RXN-12965
|
|
|
|
L-tyrosine + O2 + FADH2 <=> L-Dopa + H2O + FAD + H+
|
1.14.14
1.14.14.9
4-hydroxyphenylacetate 3-monooxygenase
|
–
–
|
| |
BRENDA:
BS428763
MetaCyc:
RXN-14990
|
|
|
|
6'-hydroxycaffeoyl-CoA <=> esculetin + CoA
|
not assigned
|
–
|
| |
MetaCyc:
RXN-16763
|
|
|
|
4-coumaroyl-CoA + 2-oxoglutarate + O2 <=> 2,4-dihydroxycinnamoyl-CoA + succinate + CO2
|
1.14.11.62
trans-4-coumaroyl-CoA 2-hydroxylase
|
–
|
| |
BRENDA:
BR52905
KEGG:
R12306
MetaCyc:
RXN-12963
|
|
|
|
trans-6-hydroxyferuloyl-CoA <=> scopoletin + CoA
|
not assigned
|
–
|
| |
KEGG:
R11550
MetaCyc:
RXN-12350
|
|
|
|
L-tyrosine <=> p-coumaric_acid + NH3
|
4.3.1.23
tyrosine ammonia-lyase
4.3.1.24
phenylalanine ammonia-lyase
4.3.1.25
phenylalanine/tyrosine ammonia-lyase
5.4.3.6
tyrosine 2,3-aminomutase
|
–
–
–
–
|
| |
BRENDA:
BR48920
KEGG:
R00737
MetaCyc:
RXN-9697
SABIO-RK:
1100
|
|
|
|
feruloyl-CoA + 2-oxoglutarate + O2 <=> trans-6-hydroxyferuloyl-CoA + succinate + CO2
|
1.14.11.61
feruloyl-CoA 6-hydroxylase
|
–
|
| |
BRENDA:
BR52666
KEGG:
R11549
MetaCyc:
RXN-12349
|
|
|
|
caffeoyl-CoA + 2-oxoglutarate + O2 <=> 6'-hydroxycaffeoyl-CoA + succinate + CO2
|
1.14.11
1.14.11.61
feruloyl-CoA 6-hydroxylase
|
–
–
|
| |
BRENDA:
BS447257
MetaCyc:
RXN-16762
|
|
|
|
p-coumaric_acid + O2 + FADH2 <=> caffeic_acid + H2O + FAD + H+
|
1.14.14
1.14.14.9
4-hydroxyphenylacetate 3-monooxygenase
|
–
–
|
| |
BRENDA:
BS428032
MetaCyc:
RXN-14988
|
|
|
|
L-Dopa <=> caffeic_acid + NH3
|
4.3.1.23
tyrosine ammonia-lyase
4.3.1.25
phenylalanine/tyrosine ammonia-lyase
|
–
–
|
| |
BRENDA:
BS445601
MetaCyc:
RXN-14987
|
|
|
|
caffeic_acid + CoA + ATP <=> caffeoyl-CoA + AMP + diphosphate
|
6.2.1.12
4-coumarate---CoA ligase
|
–
|
| |
BRENDA:
BS26
KEGG:
R01943
MetaCyc:
RXN-1126
SABIO-RK:
12842;
1996
|
|
|
|
S-adenosyl-L-methionine + caffeoyl-CoA <=> H+ + feruloyl-CoA + S-adenosyl-L-homocysteine
|
2.1.1.104
caffeoyl-CoA O-methyltransferase
|
–
|
| |
BRENDA:
BR43863
KEGG:
R01942
MetaCyc:
CAFFEOYL-COA-O-METHYLTRANSFERASE-RXN
|
|
